Table 1. Significant difference of functional connectivity of the eight RSNs between HC and TLEG.
RSNs | Patients with TLE vs Controls | |||
Brain regions | Brodmann | Peak locationMNI (x , y, z) | Peak t value | |
RSN1 | Left Posterior Cingulate | 26 | −2, −41,28 | 7.16 |
Left Angular Gyrus | 39 | −39, −54,33 | 5.54 | |
Left Superior Parietal Lobule | 7 | −35, −55,48 | 5.45 | |
RSN2 | Left Superior Frontal Gyrus | 6 | 0,48,48 | 7.51 |
Left Anterior Cingulate | 11,24 | −6,36,24 | 5.82 | |
Right Superior Frontal Gyrus | 6 | 6,15,72 | 5.70 | |
Left Superior Frontal Gyrus | 6,8 | −3,24,59 | 4.37 | |
RSN3 | Left Postcentral Gyrus | 3 | −45, −36,60 | 13.56 |
Left Superior Parietal Lobule | 2 | −21, −44,63 | 10.54 | |
Right Postcentral Gyrus | 1,3 | 51, −18,57 | 8.56 | |
Left Precentral Gyrus | 6 | −34, −22,63 | 8.42 | |
Left Inferior Parietal Lobule | 40 | −35, −48,54 | 8.13 | |
Right Inferior Parietal Lobule | 40 | 35, −39,51 | 7.19 | |
Right Superior Parietal Lobule | 7 | 24, −59,57 | 5.23 | |
RSN4 | Left Superior Frontal Gyrus | 9 | −21,42,18 | 6.87 |
Right Superior Frontal Gyrus | 9 | 18,45,18 | 5.07 | |
RSN5 | Left Middle Frontal Gyrus | 6 | −30,12,66 | 6.51 |
Left Superior Frontal Gyrus | 8 | −11,31,55 | 4.35 | |
RSN6 | Right Superior Frontal Gyrus | 9,10 | 21,42,15 | 6.67 |
Right Inferior Parietal Lobule | 40 | 47, −48,52 | 5.74 | |
Left Inferior Parietal Lobule | 39 | −51, −63,39 | 4.94 | |
RSN7 | Left superior Occipital Gyrus | 17 | −8, −99,9 | 8.12 |
Left Calcarine | 17 | −1, −98,9 | 5.63 | |
Left Lingual Gyrus* | 17 | −3, −90,0 | 11.95 | |
Left Cuneus* | 18 | −9, −102,9 | 10.39 | |
Right Lingual Gyrus* | 18 | 15, −84, −12 | 8.54 | |
RSN8 | Left Insula | 13 | −42,6, −3 | 7.14 |
Right Inferior Frontal Gyrus | 47 | 42,15, −6 | 7.08 | |
Right Insula | 13 | 42, −18,0 | 6.37 | |
Left Superior Temporal Gyrus | 38 | −24,3, −21 | 5.85 | |
Right Lentiform Nucleus | 34 | 21,18, −3 | 5.44 | |
Left Subcallosal Gyrus | 40 | −24,9, −9 | 4.45 | |
Left Postcentral Gyrus | 22 | −50, −24,15 | 4.59 |
Note: * regions represented increased functional connectivity in TLE in contrast to HC.