Table 2. Significant difference of functional connectivity of the eight RSNs between HC and MPEG.
RSNs | Patients with MPE vs Controls | |||
Brain regions | Brodmann | Peak locationMNI (x , y, z) | Peak t value | |
RSN1 | Left Posterior Cingulate | 23 | −6, −44,27 | 15.21 |
Right Posterior Cingulate | 23 | 7, −48,30 | 11.05 | |
Left Precuneus Gyrus | 23 | −4, −62,28 | 10.50 | |
Right Precuneus Gyrus | 31 | 5, −64,29 | 6.23 | |
Left Angular | 39 | −46, −66,29 | 4.56 | |
RSN2 | Left Superior Frontal Gyrus, | 8 | 0,48,48 | 13.28 |
Left Anterior Cingulate | 24 | −5,23,29 | 8.03 | |
Right Anterior Cingulate | 24,33 | 9,15,21 | 5.70 | |
RSN3 | Left Supplementary Motor Area | 6 | −1, −15,53 | 7.60 |
Right Cingulate Gyrus | 24,32 | 3,6,42 | 5.79 | |
Left Cingulate Gyrus | 24 | −5,3,35 | 5.43 | |
Left Postcentral Gyrus | 3 | −31, −36,55 | 4.72 | |
RSN4 | Left Anterior Cingulate | 32 | −3,33, −3 | 14.77 |
Left Medial Frontal Gyrus | 11 | −12,24, −9 | 11.72 | |
Right Medial Frontal Gyrus | 11 | 5,48, −12 | 8.80 | |
RSN5 | Left Inferior Parietal Lobule | 39 | −45, −50,39 | 10.73 |
Left Inferior Frontal Gyrus | 45 | −41,43,16 | 8.98 | |
Left Middle Temporal Gyrus | 37 | −42, −57,24 | 5.74 | |
RSN6 | Right Inferior Parietal Lobule | 40 | 54, −54,39 | 9.76 |
Right Angular | 39 | 56, −54,34 | 8.38 | |
Right Anterior Cingulate | 10,32 | 15,42,0 | 7.65 | |
Right Superior Frontal Gyrus | 8 | 9,42,45 | 7.00 | |
Right Anterior Cingulate | 32 | 18,27, −9 | 5.90 | |
Right Inferior Frontal Gyrus* | 44 | 49,15,34 | 8.94 | |
RSN7 | Left Superior Occipital Gyrus | 17 | −8, −98,10 | 10.98 |
Right Superior Occipital Gyrus | 17 | 21, −99,7 | 9.95 | |
Left middle Occipital Gyrus* | 18 | −31, −89,7 | 12.31 | |
Right middle Occipital Gyrus* | 19 | 39, −77,10 | 11.86 | |
Right Lingual Gyrus* | 17 | 8, −64,11 | 9.60 | |
Left Cuneus* | 18 | −12, −95,9 | 8.92 | |
Right Cuneus* | 17 | 9, −95,5 | 6.90 | |
RSN8 | Left Insula | 13 | −42,9, −3 | 12.93 |
Left Parahippocampal Gyrus | 28,34 | −24, −9, −12 | 8.99 | |
Right Insula | 13 | 36,12, −6 | 6.61 | |
Right Superior Temporal Gyrus | 22 | 51, −5,0 | 4.45 |
Note: * regions represented increased functional connectivity in MPE in contrast to HC.