Table 2.
Human germline genes most similar to the 10 selected scFvs.
| VH | VL | |||||
|---|---|---|---|---|---|---|
| scFv | V | D | J | V | J | GI (%) |
| 2A3 | IGHV4-28*01 | IGHD3-22*01 | IGHJ4*02 | IGKV1D-13*01 | IGKJ3*01 | 88 |
| 1G7 | IGHV3-11*03 | IGHD2-2*03 | IGHJ5*02 | IGKV1-6*01 | IGKJ4*01 | 82 |
| 2A6 | IGHV4-4*03 | IGHD5-12*01 | IGHJ4*02 | IGKV1-9*01 | IGKJ1*01 | 88 |
| 2F2 | IGHV1-8*01 | IGHD6-25*01 | IGHJ5*02 | IGKV1-39*01 | IGKJ1*01 | 87 |
| 2G10 | IGHV3-66*02 | IGHD3-9*01 | IGHJ4*02 | IGKV1-33*01 | IGKJ1*01 | 85 |
| 2H8 | IGHV1-2*02 | IGHD2-8*02 | IGHJ5*02 | IGKV3-11*01 | IGKJ2*04 | 88 |
| 3C6 | IGHV5-51*01 | IGHD1-1*01 | IGHJ5*02 | IGKV1-12*01 | IGKJ4*01 | 84 |
| 3C11 | IGHV1-2*02 | IGHD2-8*02 | IGHJ5*02 | IGKV1-5*03 | IGKJ1*01 | 86 |
| 3G12 | IGHV3-23*04 | IGHD6-13*01 | IGHJ4*02 | IGKV1-27*01 | IGKJ3*01 | 86 |
| 2D1 | IGHV4-61*02 | IGHD6-13*01 | IGHJ4*02 | IGKV4-1*01 | IGKJ4*01 | 85 |
Human germline genes most similar to the genes coding for the 10 selected scFvs were retrieved by IMGT /DomainGapAlign. The germinality index (GI) of each scFv (VH+VL) is indicated in the right column.