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EGFR gene copy analysis by three-dimensional FISH
| No. of Patients (%), (n = 36) | ||||
|---|---|---|---|---|
| Mean copy number | < 2.5 | ≥ 2.5- < 4.0 | ≥ 4.0- < 6.0 | ≥ 6.0 |
| (normal) | (low level) | (high level) | (amplification) | |
| EGFR | 8 (22%) | 20 (56%) | 7 (19%) | 1 (3%) |
| CEP7 | 11 (31%) | 22 (61%) | 2 (6%) | 1 (3%) |
| Ratio | < 1.1 | ≥ 1.1-1.5 | ||
| EGFR/CEP7 | 22 (61%) | 14 (39%) | ||
Abbreviation: FISH fluorescence in situ hybridisation
