Table 1. Summary of a likelihood ratio test using PAML for positive selection in the SnTox1 gene.
Model pairs | dN/dS | Log likelihood (l)a | P b | Positively selected codons c | Posterior prob. |
M1a (nearlyneutral) | 0.52 | −553.98 | 48 | 0.975 | |
M2a (selection) | 4.49 | −546.04** | 68 | 0.978 | |
M1a/M2a LRT | <0.001 | 72 | 0.997 | ||
M7 (beta) | 0.50 | −554.07 | 106 | 0.974 | |
M8 (beta & ω) | 4.49 | −546.127** | |||
M7/M8 LRT | <0.001 |
Asterisks indicate which model resulted in a statistically higher likelihood score for the SnTox1 codon alignment.
P-value for the likelihood ratio test (LRT) between the log-likelihoods of comparable models. In both cases the null hypothesis is rejected in favor of the selection model.
Specific codons within the amino acid sequence were tested for positive selection. Positively selected codons with a Bayes Empirical Bayes posterior probability higher than 0.95 are listed on the right half of the table [78].