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. 2012 Jan 5;8(1):e1002466. doi: 10.1371/journal.ppat.1002466

Table 1. siRNAs perturbing infectious HCV secretion.

Percent Inhibition*
Gene Infectious HCV Host Gene RNA Intra-:Extra- cellular virus Function
SAR1A 80 64 4.10 ER -> Golgi
CYTH3 87 75 3.35 Golgi function
CLINT1 77 70 2.99 Golgi sorting
PI4KB 90 76 13.73 Golgi sorting
PRKD1 73 75 3.43 Golgi sorting
AP1M1 85 81 2.32 Golgi Sorting
PACSIN3 76 91 2.71 Vesicle trafficking
ARF3 75 73 2.18 Golgi trafficking
RAB11A 82 61 3.51 Exocytosis
RAB3D 69 80 9.94 Exocytosis
VAMP1 81 77 5.04 Exocytosis
RHOA 75 71 2.65 Actin/remodeling
GIT1 71 69 3.04 Actin/remodeling
WAS 71 91 5.87 Actin/remodeling

*as compared to siIRRelevant treated cells.