Table 1.

Endpoints from study investigating single agent celecoxib by Mantovani et al [21]

	Baseline	After treatment	p values
TNF-alpha (pg/ml)	36.8 ± 14.1	29.9 ± 12.2	0.007
LBM (Kg)	45.4 ± 6.7	45.8 ± 6.6	< 0.0001
QoL	66.3 ± 19.9	75.3 ± 10.1	0.024
ECOG PS	1.5 ± 0.67	1.2 ± 0.59	0.0023
GPS	1.3 ± 0.77	0.8 ± 0.7	0.0004
Grip strength	20. 8 ± 4.7	24.0 ± 5.5	0.004

TNF-alpha = Tumour Necrosis Factor-alpha, LBM = Lean body mass, QoL = Quality of life, ECOG PS = Eastern Cooperative Oncology Group (ECOG) Performance status, GPS = Glasgow prognostic score. Data are reported as mean ± SD.