Table 1.
HIV negative Normal Pap test 1 (n=17) | HIV positive Normal Pap test (n=18) | HIV positive HSIL on Pap test 2 (n=13) | P-value | |
---|---|---|---|---|
Mean Age ± sd 3 | 32 ± 12 | 43 ± 11 | 39 ± 8 | 0.006 |
Smoking | 1 (6%) | 1 (6%) | 2 (15%) | 0.66 |
| ||||
Receiving ART 4 | - | 15 (83%) | 9 (69%) | 0.41 |
Median nadir CD4 T cells per mm3 (range) 5 | - | 228 (31 - 301) | 224 (80 - 302) | 0.89 |
Median CD4 T cells per mm3 at time of study(range) | - | 402 (181 - 815) | 327 (183 - 660) | 0.07 |
Median plasma HIV-1 RNA copies per ml at time of study (range) | - | 50 (50–240,000) | 23,000 (50- 630,000) | 0.03 |
Women with normal Pap test had normal cervical cytology by Bethesda Classification system and negative Digene HCII test for high risk HPV.
Women with high grade squamous intraepithelial lesions (HSIL) by Bethesda Classification system also had a positive test by Digene HCII for high risk HPV.
Standard deviation (sd)
Antiretroviral therapy (ART)
The nadir CD4 T cell count is the lowest documented CD4 T cell count for an individual patient