Figure 1.
Representative patient with an acute episode of OPC pre- and post- antifungal treatment. (A) Evaluation of fungal burden over time. Arrows indicate when biopsies were taken over the course of study. CFU=colony forming units, BM=buccal mucosa, WM=whole mouth. (B) Immunohistochemical evaluation of CD8+ T cells and E-cadherin expression pre- and post-treatment with antifungal therapy. Magnification 10x. Red arrows point to positive staining. E=epithelium, LP=lamina propria. Scores for relative expression (+ to ++++) are provided for LP and/or E.