Figure 3.

Connection of Oct4 with multiple epigenetic regulatory pathways. Summary of major protein complexes (red dotted circles) associated with the Oct4 interactome. Big filled circles with color are Oct4-interacting proteins that are also the RNAi hits from published genome-wide RNAi studies (see also Figure 5). Small filled circles with color are Oct4-interacting proteins identified in this study. Other components of the complexes not present in the Oct4 interactome are shown in gray small circles.