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. Author manuscript; available in PMC: 2013 Mar 22.
Published in final edited form as: Chirality. 2011 Sep 22;23(10):891–896. doi: 10.1002/chir.21005

Fig. 5.

Fig. 5

Enantioselective inhibition of human CYP2C19 by naringenin. A range of concentrations of rac-naringenin (open circle), (R)-naringenin (dark square), or (S)-naringenin (dark triangle) was incubated with recombinant human CYP2C19 (7.5 nM) and substrate CEC at 37°C for 30 min and enzyme activity was determined in three independent experiments. Individual points represent the mean of duplicate incubations. CEC, 3-cyano-7-ethoxycoumarin.