Table 2.

Demographics and risk factors of KPC-producing K. pneumoniae cases.

Demographics/risk factors	KPC group	%	Control group	%	Odds Ratio	95% Confidence Interval	p-value
Apache II score	21 a	(3–44) b	14 a	(1–45) b	1.11	(1.05, 1.17)	0.0001
Male	8	40.00	92	52.27	0.61	(0.24, 1.56)	0.30
Age >60	12	60.00	95	54.29	1.26	(0.49, 3.24)	0.63
Immunocompromised	13	65.00	93	52.84	1.66	(0.63, 4.35)	0.30
Caucasian	4	21.05	96	67.61	0.13	(0.04, 0.41)	0.0005
Hispanic	3	15.79	13	9.15	1.86	(0.48, 7.24)	0.37
Admitted from nursing home	6	30.00	28	16.00	2.25	(0.80, 6.35)	0.13
Number of days hospitalized before infection	20 a	(0–323) b	1 a	(0–141) b	1.03	(1.01, 1.05)	0.0006
Any hospitalization in past year	16	80.00	141	80.11	0.99	(0.31, 3.16)	0.99
Any ICU admission in past year	9	45.00	54	30.68	1.85	(0.72, 4.72)	0.20
Any surgery in past year	13	65.00	64	36.36	3.25	(1.23, 8.56)	0.02
Dialysis in past year	1	5.00	8	4.55	1.11	(0.13, 9.32)	0.93
Outpatient intravenous therapy in past year	3	15.00	16	9.09	1.76	(0.47, 6.68)	0.40
Prior surgery within 30 days	3	15.00	26	14.77	1.02	(0.28, 3.72)	0.98
Antibiotics in 30 days prior to enrollment	17	85.00	40	22.73	19.3	(5.37, 69.07)	<.0001
Carbapenem c	5	25.00	4	2.27	14.3	(3.48, 59.10)	0.0002
Ampicillin/sulbactam	2	10.00	11	6.25	1.67	(0.34, 8.12)	0.53
Fluoroquinolone d	2	10.00	13	7.39	1.39	(0.29, 6.67)	0.68
Cefepime	9	45.00	8	4.55	17.2	(5.54, 53.23)	<.0001
Ceftriaxone	3	15.00	2	1.14	15.3	(2.40, 98.27)	0.004
Piperacillin/tazobactam	0	0.00	7	3.98	0.90	(0.00, 6.33)	0.93
Chronic renal failure	6	30.00	21	11.93	3.16	(1.10, 9.13)	0.03
Diabetes	6	30.00	41	23.30	1.41	(0.51, 3.91)	0.51
Chronic obstructive lung disease	4	20.00	29	16.48	1.27	(0.40, 4.07)	0.69
Cardiovascular disease	5	25.00	41	23.30	1.10	(0.38, 3.20)	0.86
Peripheral vascular disease	1	5.00	3	1.70	3.04	(0.30, 30.65)	0.35
Cerebrovascular disease	3	15.00	13	7.39	2.21	(0.57, 8.55)	0.25
Peptic ulcer disease	0	0.00	9	5.11	0.68	(0, 4.60)	0.74
liver disease	2	10.00	17	9.66	1.04	(0.22, 4.87)	0.96
Malignancy	8	40.00	41	23.30	2.20	(0.84, 5.74)	0.11
Solid organ malignancy	7	35.00	36	20.45	2.09	(0.78, 5.63)	0.14
Transplant	1	5.00	17	9.66	0.49	(0.06, 3.91)	0.50
Tracheostomy tube at enrollment	8	40.00	17	9.66	6.24	(2.24, 17.38)	0.0005
Gastrostomy tube at enrollment	9	45.00	7	3.98	19.8	(6.19, 63.06)	<.0001
Indwelling urinary catheter at enrollment	5	25.00	25	14.20	2.01	(0.67, 6.03)	0.21
Vascular catheter at enrollment	15	75.00	101	57.39	2.23	(0.78, 6.40)	0.14

^aMedian.

^bRange.

^cErtapenem, imipenem, meropenem.

^dCiprofloxacin, levofloxacin, moxifloxacin.