TABLE 4.
Quintiles of GI within 3 strata of alcohol intake (g/d) |
||||||
0.16–50 | >50 to 52 | >52 to 53 | >53 to 55 | >55 | P-trend | |
Alcohol intake of 0 to <5 g/d | ||||||
Cases (n) | 807 | 981 | 1045 | 1185 | 1423 | — |
Person-years | 213,168 | 234,826 | 252,356 | 271,235 | 291,529 | — |
MV model 1 | 1.00 (reference)2 | 1.16 (1.05, 1.27) | 1.20 (1.09, 1.32) | 1.28 (1.17, 1.41) | 1.45 (1.32, 1.59) | <0.001 |
Alcohol intake of 5 to <15 g/d | ||||||
Cases (n) | 221 | 223 | 224 | 184 | 171 | — |
Person-years | 102,368 | 102,200 | 95,683 | 84,773 | 65,465 | — |
MV model 2 | 1.00 (reference) | 1.07 (0.88, 1.29) | 1.17 (0.96, 1.42) | 1.09 (0.89, 1.35) | 1.37 (1.10, 1.70) | <0.01 |
Alcohol intake of ≥15 g/d | ||||||
Cases (n) | 118 | 118 | 97 | 76 | 77 | — |
Person-years | 70,169 | 57,505 | 49,105 | 39,737 | 31,760 | — |
MV model 3 | 1.00 (reference) | 1.21 (0.93, 1.57) | 1.21 (0.91, 1.60) | 1.21 (0.89, 1.64) | 1.40 (1.03, 1.91) | 0.04 |
All MV models were adjusted for the same covariates as in Table 3. At baseline, the number of participants in each alcohol category was as follows: 53,102 for alcohol intake 0 to <5 g/d with the number of participants from quintiles 1 to 5 of GI being 9383, 9954, 10,460, 11,187, and 12,118, respectively; 18, 681 for alcohol intake 5 to <15 g/d with the number of participants from quintiles 1 to 5 of GI being 4130, 4149, 3859, 3597, and 2946, respectively; and 10,044 for alcohol intake ≥15 g/d with the number of participants from quintiles 1 to 5 of GI being 2718, 2279, 2034, 1667, and 1346, respectively. P-interaction = 0.76. GI, glycemic index; MV, multivariate; T2D, type 2 diabetes.
RR (95% CI) from Cox proportional hazards models (all such values).