Figure 3.

Yeast telomerase is not recruited at long T₂AG₃ ends in wild-type cells, but is bound to these ends in a tbf1-Δi mutant strains. Analysis by ChIP of Est1–Myc and Est2–Myc binding after HO induction at 60 bp T₂AG₃, 250 bp T₂AG₃, or non-TG ends (as marked), in wild-type cells (top panels) or in tbf1-Δi mutant strains (bottom panels). HO constructs, PCR probes, ChIP methods, and statistical analysis were as described in Figures 1 and 2, and in Materials and methods.