Table 1.
Regions active during social exclusion vs the control task (controlling for ethnicity)
| Anatomical Region | BA | x | y | z | t | k | P | |
|---|---|---|---|---|---|---|---|---|
| Anterior insula | R | 42 | 27 | −9 | 6.67 | 2518 | <0.0001 | |
| Anterior insula | L | −45 | 18 | −15 | 4.28 | 139 | <0.0005 | |
| dACC | 24 | 0 | 15 | 27 | 4.59 | 16 | <0.0001 | |
| Lateral occ. cortex | 37 | R | 54 | −69 | 3 | 12.86 | 3235 | <0.0001 |
| TPJ | 40 | R | 63 | −42 | 24 | 9.34 | 3235 | <0.0001 |
| Fusiform gyrus | 37 | R | 39 | −51 | −15 | 8.41 | 3235 | <0.0001 |
| Precuneus | 7 | R | 9 | −54 | 60 | 5.27 | 3235 | <0.0001 |
| Lateral occ. cortex | 39 | L | −48 | −72 | 12 | 11.29 | 780 | <0.0001 |
| TPJ | 40 | L | −57 | −48 | 27 | 6.34 | 780 | <0.0001 |
| SFG | 6 | R | 42 | 3 | 54 | 7.26 | 2848 | <0.0001 |
| MPFC | 10 | 0 | 54 | 15 | 5.89 | 2848 | <0.0001 | |
| DLPFC | 45 | R | 45 | 24 | 24 | 4.87 | 2848 | <0.0001 |
| DMPFC | 9 | R | 3 | 54 | 39 | 4.43 | 2848 | <0.0005 |
| Striatum | R | 6 | 6 | 9 | 7.07 | 313 | <0.0001 | |
| Brainstem | L | −3 | −30 | −3 | 5.40 | 140 | <0.0001 | |
| Cerebellum | L | −15 | −78 | −30 | 5.40 | 426 | <0.0001 | |
| Temporal pole | 28 | L | −30 | 9 | −24 | 5.12 | 160 | <0.0001 |
| SFG | 6 | L | −24 | 0 | 69 | 5.03 | 187 | <0.0001 |
| Fusiform gyrus | 37 | L | −39 | −60 | −12 | 4.93 | 132 | <0.0001 |
| Cerebellum | R | 6 | −42 | −36 | 4.53 | 55 | <0.0005 | |
| SPL | 19 | L | −24 | −72 | 36 | 4.44 | 70 | <0.0005 |
| DLPFC | 45 | L | −42 | 15 | 24 | 4.43 | 64 | <0.0005 |
| Amygdala | R | 15 | −3 | −15 | 3.88 | 27 | <0.001 | |
| VLPFC | 10 | R | 27 | 54 | 9 | 3.18 | 13 | <0.005 |
| rACC | 24 | R | 12 | 27 | 21 | 3.17 | 13 | <0.005 |
Note: Regions identified a priori (e.g. dACC, anterior insula) are listed if they were significant at P < 0.005, 10 voxels or greater (k-values listed for these regions were taken from this thresholding map). Other regions listed were not the primary focus of this investigation but were still significant after correction for multiple comparisons (k-values listed for these regions were taken from the thresholding map at P < 0.05, 10 voxels, FDR-corrected). The individual P-values listed indicate the level of significance that each particular region met. BA refers to putative Brodmann’s Area; L and R refer to left and right hemispheres; x, y and z refer to MNI coordinates; t refers to the t-score at those coordinates (local maxima); k refers to the number of voxels in each significant cluster. The following abbreviations are used for the names of specific regions: dorsal anterior cingulate cortex (dACC), occipital (Occ.), temporoparietal junction (TPJ), superior frontal gyrus (SFG), medial prefrontal cortex (MPFC), dorsolateral prefrontal cortex (DLPFC), dorsomedial prefrontal cortex (DMPFC), superior parietal lobule (SPL), ventrolateral prefrontal cortex (VLPFC) and rostral anterior cingulate cortex (rACC).