Table 3.
Regions showing a correlation between the BES-Affective Empathy subscale and BOLD response for the contrasts of interest across all participants
| Brain region | BA | L/R | Peak voxel | k | z | FWE-corrected P-value |
|---|---|---|---|---|---|---|
| BES-affective (Affective ToM > PC) | ||||||
| Positive relationship—none | ||||||
| Negative relationship | ||||||
| Premotor cortex | 6 | R | 26 −6 50 | 192 | 5.20 | 0.009 |
| Ventrolateral prefrontal cortex | 47 | R | 44 40 −8 | 316 | 4.96 | <0.001 |
| 46 | R | 42 32 16 | 4.42 | |||
| 46/47 | R | 44 36 4 | 3.91 | |||
| Cerebellum, posterior lobe | – | L | −32 −60 −40 | 389 | 4.93 | <0.001 |
| L | −22 −66 −46 | 4.85 | ||||
| L | −32 −70 −30 | 3.80 | ||||
| BES-affective (Cognitive ToM > PC) | ||||||
| Positive relationship | ||||||
| Parahippocampal gyrus ext. hippocampus | – | L | −22 −18 −24 | 182 | 4.95 | 0.012 |
| – | L | −12 −18 −24 | ||||
| Negative relationship—none | ||||||
| BES-affective (Affective ToM > Cognitive ToM)a | ||||||
| Positive relationship—none | ||||||
| Negative relationship | ||||||
| Post-central gyrus | 40 | L | −58 −28 20 | 234 | 4.83 | 0.004 |
| Ventrolateral prefrontal cortex | 45 | R | 56 14 2 | 248 | 4.21 | 0.003 |
| ext. insula | 13 | R | 46 12 2 | 4.05 | ||
| ext. superior temporal gyrus | 22 | R | 62 0 4 | 3.79 | ||
| Posterior insula | 13 | L | −40 −8 4 | 593 | 4.11 | <0.001 |
| 13 | L | −38 −2 10 | 4.08 | |||
| ext. superior temporal gyrus | 22 | L | −50 2 2 | 3.93 |
aCognitive ToM > Affective ToM correlations with BES are the reverse of those shown here. Results are significant at P < 0.05 FWE-corrected at the cluster level.
L/R = left/right, peak voxel = MNI xyz co-ordinates, k = cluster size.