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. 2010 Dec 30;8(2):170–176.

Table 1.

Anti-trichomonal activities of Eugenia uniflora leaf methanolic extract, its partition and VLC fractions.

Extract/Fractions/Drug 24 hrs 48 hrs


LC50 (µg/ml) LC90 (µg/ml) LC50 (µg/ml) LC90 (µg/ml)
MeOH (A) 61.70±1.65 386.84±4.32 55.15± 2.17 302.93±9.54
n-Hexane (B1) 40.00±2.24*, 271.10±5.72*, 70.52± 3.41 551.69±2.37*,
CHCl3 (B2) 27.60± 3.76* 126.95±2.82*, 18.67± 3.29* 68.82± 5.41*
EtOAc (B3) 41.51± 4.48 194.79±7.57*, 24.18± 1.37* 86.39±2.04*
BuOH (B4) 58.62± 2.56 353.79±10.75 52.31±3.71 427.39±9.65*,
Aqueous (B5) 103.19±0.96*, 704.65±2.66*, 59.10± 8.34 592.06± 2.01*,
C1 35.08±2.89* 238.50± 9.17*, 18.05± 5.09* 106.90± 5.21*,
C2 36.43± 2.73*, 265.34± 9.43*, 32.69± 4.66*, 156.95± 5.68*
C3 222.83± 9.26* 1063.57±5.81*, 40.88± 4.95 263.50± 4.76
C4 75.10± 4.64*, 747.77± 3.14*, 206.08± 9.86* 1010.40±10.56*,
C5 125.69±1.30*, 1274.49±4.89*, 27.12± 7.00 168.75±11.11*
Metronidazole 13.67± 0.87* 42.86± 2.60* 14.04± 5.85* 61.37±8.69*

A: Methanolic extract; B1: N-hexane, B2: Chloroform, B3: Ethylacetate, B4: Butanol, B5: Aqueous partition fractions; C1–5: VLC subfractions of the combined most active partition fractions B2 and B3. N = 9; p < 0.05; *: LC50 and LC90 vs MeOH, : LC50 and LC90 vs metronidazole. LC50 and LC90: Values ± SEM.