Table 1.
Anti-trichomonal activities of Eugenia uniflora leaf methanolic extract, its partition and VLC fractions.
| Extract/Fractions/Drug | 24 hrs | 48 hrs | ||
| LC50 (µg/ml) | LC90 (µg/ml) | LC50 (µg/ml) | LC90 (µg/ml) | |
| MeOH (A) | 61.70±1.65† | 386.84±4.32† | 55.15± 2.17† | 302.93±9.54† |
| n-Hexane (B1) | 40.00±2.24*,† | 271.10±5.72*,† | 70.52± 3.41† | 551.69±2.37*,† |
| CHCl3 (B2) | 27.60± 3.76* | 126.95±2.82*,† | 18.67± 3.29* | 68.82± 5.41* |
| EtOAc (B3) | 41.51± 4.48† | 194.79±7.57*,† | 24.18± 1.37* | 86.39±2.04* |
| BuOH (B4) | 58.62± 2.56† | 353.79±10.75† | 52.31±3.71† | 427.39±9.65*,† |
| Aqueous (B5) | 103.19±0.96*,† | 704.65±2.66*,† | 59.10± 8.34† | 592.06± 2.01*,† |
| C1 | 35.08±2.89* | 238.50± 9.17*,† | 18.05± 5.09* | 106.90± 5.21*,† |
| C2 | 36.43± 2.73*,† | 265.34± 9.43*,† | 32.69± 4.66*,† | 156.95± 5.68* |
| C3 | 222.83± 9.26* | 1063.57±5.81*,† | 40.88± 4.95† | 263.50± 4.76† |
| C4 | 75.10± 4.64*,† | 747.77± 3.14*,† | 206.08± 9.86* | 1010.40±10.56*,† |
| C5 | 125.69±1.30*,† | 1274.49±4.89*,† | 27.12± 7.00 | 168.75±11.11* |
| Metronidazole | 13.67± 0.87* | 42.86± 2.60* | 14.04± 5.85* | 61.37±8.69* |
A: Methanolic extract; B1: N-hexane, B2: Chloroform, B3: Ethylacetate, B4: Butanol, B5: Aqueous partition fractions; C1–5: VLC subfractions of the combined most active partition fractions B2 and B3. N = 9; p < 0.05; *: LC50 and LC90 vs MeOH, †: LC50 and LC90 vs metronidazole. LC50 and LC90: Values ± SEM.