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. 2011 Nov 4;19(1):87–95. doi: 10.1038/cdd.2011.146

Table 1. Examples from various organisms where loss of the autophagic machinery suppresses physiological cell death.

Organism Tissue/cells Autophagy inhibition
Arabidopsis Tracheary elements Atg5 mutant
Dictyostelium Fruiting body formation Atg1 mutants
Drosophila Removal of larval salivary glands Atg mutants
Drosophila Removal of larval midgut Atg2, Atg18 mutants and Atg1, Atg18 knockdown
Mammals Ras-expressing HOSE cells Atg5 and Atg7 knockdown
Mammals HCN after insulin withdrawal Atg7 knockdown