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Using 3 µM SEA0400 to treat cells shortened AP duration (A) and reduced INIFE (B). The residual current (C) and the residual depolarization (D) were significantly reduced (n=7 cells, t-test, p<0.05*), demonstrating a predominant influence of INCX on these features. Panel E shows a universal correlation (R=0.917) between the magnitude of residual current and residual depolarization under all experimental conditions tested.
