Table III. Test characteristics of mammography and breast ultrasound in predicting pathologic complete response following neoadjuvant chemotherapy (n=104).
| Test characteristic | Mammography (95% CI) |
Breast Ultrasound (95% CI) |
|---|---|---|
| Sensitivity | 54.2 (34.3–73.0) | 45.8 (25.6–67.2) |
| Specificity | 86.3 (77.4–92.6) | 93.8 (86.7–97.7) |
| Predictive value positive | 54.2 (34.3–73.0) | 68.8 (43.7–87.5) |
| Predictive value negative | 86.3 (77.4–92.6) | 85.2 (76.6–91.5) |
| Likelihood ratio of a positive test | 3.9 | 7.3 |
| Likelihood ratio of a negative test | 0.53 | 0.58 |
| Kappa | 0.40 (0.18–0.62) | 0.45 (0.24–0.66) |
| PABAK | 0.58 | 0.65 |
| Probability of a pCR based on an imaging CR | 54.3 | 68.9 |
| Probability of a pCR based on imaging residual disease |
13.8 | 14.8 |
95% CI: 95 percent confidence interval; PABAK: Prevalence and bias-adjusted kappa; pCR: pathologic complete response