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. 2011 Dec 16;109(1):215–220. doi: 10.1073/pnas.1113442109

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Fig. 4. — Inhibition of TGF-β signaling rescues the osteogenic differentiation in MFS cells. (A) Treatment with SB431542 rescues the osteogenic differentiation of MFS cells. In contrast, TGF-β1 inhibits dramatically osteogenic differentiation. (B) qPCR of BGLAP, a late osteogenic marker. Values are presented as above. *P < 0.05. (C) Alkaline phosphatase enzymatic activity at day 10. (D) Alizarin red staining at day 21 showing that noggin treatment does not rescue the osteogenic differentiation in MFS cells. (E) Alizarin red staining quantification.