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. 2011 Dec 16;109(1):78-83. doi: 10.1073/pnas.1111537108

Fig. 5.

Fig. 5.

Models of CALA variants with the tetrahedral intermediate (S)-1 seen in the active site. The variants shown are (A) WT, and (B) SV1CAV2. SV1CAV2 provides more space than WT to accommodate the substrate.