Table 1.
Recipient characteristics
| Characteristic | Control group (n = 843) | HBcAb+ organ recipients (n = 25) | P-value |
|---|---|---|---|
| Age, years, median (range) | 53 (18–75) | 54 (38–68) | 0.14a |
| Age, years, mean ± SD | 52.0 ± 10.3 | 55.1 ± 7.0 | |
| BMI, median (range) | 27.3 (14.4–47.3) | 29 (19.7–38.6) | 0.24a |
| BMI, mean ± SD | 27.9 ± 5.4 | 29.2 ± 5.2 | |
| Indication for transplantation, n (%) | |||
| Hepatitis C virus | 295 (35%) | 12 (48%) | |
| Hepatitis B virus | 33 (4%) | 5 (20%) | |
| Alcohol-related | 140 (17%) | 1 (4%) | |
| Primary biliary cirrhosis | 37 (4%) | 2 (8%) | |
| Primary sclerosing cholangitis | 42 (5%) | 0 | |
| Non-alcoholic steatohepatitis | 30 (4%) | 0 | |
| Cryptogenic | 71 (8%) | 3 (12%) | |
| Other | 205 (24%) | 4 (16%) | |
| MELD score, median (range) | 20 (5–50) | 22 (8–48) | 0.03a |
| MELD score, mean ± SD | 21 ± 9 | 25 ± 12 | |
| MELD score ≤30 | 737 (86%) | 17 (68%) | 0.01b |
| MELD score >30 | 106 (13%) | 8 (32%) | |
| Retransplantation, n (%) | 53 (6%) | 3 (12%) | 0.21b |
| Wait time, days, median (range) | 89 (1–2934) | 139 (18–359) | 0.04a |
| Wait time, days, mean ± SD | 230 ± 367 | 385 ± 749 | |
a
Unpaired t-test, two-tailed P-value.
b
Fisher's exact test, two-tailed P-value.
HBcAb+, hepatitis B core antibody-positive; SD, standard deviation; BMI, body mass index; MELD score, Model for End-stage Liver Disease score.