Table 2.
Structural parameters of the mouse pulmonary vasculature measured from micro-CT images of isolated mouse lungs with Y27632
| Parameter | CTL | HPH | P Value |
|---|---|---|---|
| Ltot, mm | 18.7 ± 0.9 | 18.0 ± 0.7 | 0.14 |
| NBR | 28 ± 4 | 25 ± 5 | 0.19 |
| αlung, %/mmHg | 2.3 ± 0.8 | 2.7 ± 1.0 | 0.52 |
| D(0,0), μm | 760 ± 60 | 650 ± 80* | 0.02 |
| αRPA, %/mmHg | 2.5 ± 1.1 | 1.9 ± 0.6 | 0.26 |
| CRPA, mm2/mmHg | 0.011 ± 0.004 | 0.006 ± 0.002* | 0.04 |
| RPA length, mm | 2.9 ± 0.3 | 3.1 ± 0.3 | 0.27 |
| RPA diameter, μm | 740 ± 60 | 740 ± 50 | 0.93 |
Values are means ± SD. CT, computed tomography; Ltot, total length; NBR, number of branches; αlung, whole lung distensibility; D(0,0), unstressed diameter of main pulmonary artery; αRPA, right pulmonary artery distensibility; CRPA, RPA compliance.
*
P < 0.05 vs. CTL.