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. 2010 Nov 11;110(1):199–205. doi: 10.1152/japplphysiol.01203.2009

Fig. 3.

Fig. 3.

Effect of a PKR inhibitor [2-aminopurine (2AP)] on the diaphragm force-frequency curve. Force generation was significantly lower for diaphragms from LPS-treated animals (■) than for control animals (○) (P < 0.05 for all frequencies tested). Diaphragms from animals given both 2AP, a PKR inhibitor (▵), and LPS generated forces higher than diaphragms from animals given LPS alone (P < 0.05 for all frequencies). Force generation for muscles taken from animals given the PKR inhibitor alone (▿) were similar to control levels. Values are means ± SE. *Significant statistical difference between LPS and all other groups.