Fig. 7.
Effects of A-317491 on chemoreceptors activity in developing rats. A, B, and C: typical recordings of single-unit chemosensory activities of petrosal ganglion neurons in response to normoxic-isocapnic and hypoxic-isocapnic superfusion without (control) and with A-317491 (10 μM) in developing rats at P3–P4 (A), P7–P8 (B), and P16–P21 (C). A-317491 depressed the chemosensory discharge rate in normoxic (D) and hypoxic (E) superfusion solutions. Please note the difference in the scale between D and E. Values are means ± SE; n = 5 (P3–P4), 5 (P7–P8), and 9 (P16–P21). *P < 0.05 vs. control.