Table 2.

Coefficients of heart, liver, spleen, lung and kidneys (Mean ± S.D., n = 10).

Compound		Heart	Liver	Spleen	Lung	Kidneys
Saline	H	0.602 ± 0.134	4.536 ± 0.632	0.333 ± 0.063	0.657 ± 0.105	1.333 ± 0.134
	L	0.594 ± 0.051	5.038 ± 0.534	0.368 ± 0.075	0.720 ± 0.121	1.689 ± 0.271
Blank HCO-SLN	H	0.583 ± 0.070	5.063 ± 0.453b	0.447 ± 0.124b	0.626 ± 0.109	1.364 ± 0.214
	L	0.642 ± 0.067	4.787 ± 0.813	0.426 ± 0.045	0.732 ± 0.161	1.661 ± 0.420
Til-HCO-SLN	H	0.477 ± 0.076a	5.072 ± 0.493a	0.425 ± 0.100a	0.629 ± 0.147	1.305 ± 0.226
	L	0.618 ± 0.076	4.405 ± 0.877	0.395 ± 0.075	0.732 ± 0.119	1.659 ± 0.222
Native Tilmicosin	L	0.662 ± 0.030	4.740 ± 0.600	0.359 ± 0.076	0.707 ± 0.078	1.548 ± 0.192

^a Significant difference between Til-HCO-SLN and saline treated mice, p < 0.05.

^b Significant difference between blank HCO-SLN and saline treated mice, p < 0.05.

H: high dose; L: low dose.