Table 3.

Biochemical parameters of treated mice (Mean ± S.D., n = 10).

Parameters		Saline	Til-HCO-SLN	Blank HCO-SLN	Tilmicosin (n = 5)
AST (U/L)	H	147.78 ± 37.78	157.20 ± 34.95	150.20 ± 24.15
	L	152.14 ± 18.77	143.29 ± 19.79	150.00 ± 16.12	171.00 ± 17.15
ALT (U/L)	H	44.56 ± 17.37	37.11 ± 9.18	41.00 ± 10.79
	L	42.86 ± 8.28	47.14 ± 11.05	49.57 ± 7.28	50.75 ± 0.96
ALT/AST	H	0.30 ± 0.04	0.26 ± 0.06	0.27 ± 0.05
	L	0.29 ± 0.06	0.33 ± 0.07	0.33 ± 0.05	0.30 ± 0.03
ALP (U/L)	H	136.44 ± 34.46	150.60 ± 19.57	140.29 ± 21.47
	L	121.71 ± 22.89	111.14 ± 19.30	121.50 ± 27.77	135.25 ± 17.00
TBIL (umol/L)	H	2.56 ± 1.43	1.86 ± 0.94	1.81 ± 0.89
	L	0.90 ± 0.42	0.74 ± 0.35	1.09 ± 0.41	1.38 ± 1.05
CHOL (mmol/L)	H	3.86 ± 0.48	4.21 ± 0.89	3.81 ± 0.92
	L	3.53 ± 0.54	3.54 ± 0.62	3.69 ± 0.74	3.67 ± 0.44
CREA (umol/L)	H	11.60 ± 3.27	13.13 ± 1.73	11.80 ± 2.53
	L	18.29 ± 4.57	18.00 ± 3.42	18.25 ± 1.91	17.25 ± 0.96
BUN (mmol/L)	H	7.53 ± 1.96	7.00 ± 1.12	6.72 ± 1.11
	L	8.59 ± 1.54	9.54 ± 1.48	9.47 ± 1.79	9.70 ± 0.58
TP (g/L)	H	60.90 ± 2.77	60.80 ± 2.57	56.00 ± 3.02b
	L	61.31 ± 3.57	59.37 ± 1.86	60.69 ± 2.81	61.03 ± 2.16
ALB (g/L)	H	41.49 ± 1.60	40.44 ± 2.13	38.34 ± 1.26b
	L	38.09 ± 4.89	37.06 ± 5.21	36.56 ± 3.35	38.90 ± 4.22
GLB (g/L)	H	19.41 ± 1.45	20.36 ± 1.31	17.66 ± 2.01b
	L	23.21 ± 2.18	22.31 ± 3.94	24.13 ± 2.70	22.13 ± 2.81
ALB/GLB	H	2.14 ± 0.12	1.99 ± 0.16a	2.19 ± 0.19
	L	1.71 ± 0.34	1.84 ± 0.46	1.74 ± 0.31	1.80 ± 0.41
GLU (mmol/L)	H	6.07 ± 1.68	5.98 ± 1.27	6.33 ± 1.45
	L	5.18 ± 1.78	5.02 ± 1.51	4.95 ± 1.18	5.78 ± 0.57

^a Significant difference between Til-HCO-SLN and saline treated mice, p < 0.05.

^b Significant difference between blank HCO-SLN and saline treated mice, p < 0.05.

Abbreviations: H: high dose; L: low dose; AST: aspartate aminotransferase; ALT: serum alanine aminotransferas; ALP: alkaline phosphatase; TBIL: total bilirubin; CHOL: cholesterol esters; CREA: creatinine; BUN: blood urea nitrogen; TP: total proteins; ALB: albumin; GLB: globulin; GLU: glucose.