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. 2011 Nov 20;8:33. doi: 10.1186/1743-8977-8-33

Table 4.

Hematological parameters of treated mice (Mean ± S.D., n = 10).

Parameters Saline Til-HCO-SLN Blank HCO-SLN Tilmicosin (n = 5)
WBC (109/L) H 5.51 ± 1.55 5.52 ± 1.68 4.95 ± 1.39
L 5.89 ± 1.80 5.05 ± 1.06 5.22 ± 0.93 5.16 ± 0.78
RBC H 8.56 ± 1.30 7.58 ± 1.40 7.07 ± 1.14b
(1012/L) L 9.64 ± 0.79 9.58 ± 0.96 9.63 ± 0.56 9.08 ± 0.69
HCT (L/L) H 0.44 ± 0.05 0.40 ± 0.03 0.36 ± 0.05b
L 0.59 ± 0.09 0.61 ± 0.07 0.58 ± 0.06 0.57 ± 0.07
MCV (fL) H 51.01 ± 2.69 51.06 ± 2.10 51.72 ± 4.05
L 60.37 ± 5.74 63.18 ± 4.22 60.63 ± 5.34 62.47 ± 4.76
HGB (g/L) H 141.44 ± 10.48 129.89 ± 10.25 119.43 ± 15.80b
L 153.63 ± 9.97 155.00 ± 12.00 153.38 ± 6.02 147.80 ± 4.21
MCH (pg) H 16.84 ± 2.33 16.44 ± 1.67 16.99 ± 1.77
L 15.96 ± 0.46 16.21 ± 0.57 15.94 ± 0.54 16.30 ± 0.80
MCHC (g/L) H 329.33 ± 32.11 320.70 ± 22.14 328.00 ± 19.47
L 266.88 ± 29.78 257.13 ± 15.75 264.50 ± 23.68 262.40 ± 27.93
PLT (109/L) H 873.89 ± 139.28 812.29 ± 157.35 802.00 ± 154.55
L 971.13 ± 145.25 967.63 ± 171.96 925.88 ± 219.88 972.60 ± 233.96
MPV (fL) H 6.74 ± 1.78 6.50 ± 1.14 6.25 ± 1.16
L 5.43 ± 0.29 5.28 ± 0.21 5.25 ± 0.22 5.32 ± 0.38
PCT (L/L) H 0.57 ± 0.21 0.47 ± 0.10 0.40 ± 0.11b
L 0.53 ± 0.07 0.57 ± 0.09 0.55 ± 0.11 0.56 ± 0.06
RDW (fL) H 11.83 ± 3.81 11.70 ± 2.28 11.75 ± 1.74
L 17.21 ± 0.79 18.00 ± 1.90 17.47 ± 2.02 17.72 ± 1.37
NEU (%) H 14.75 ± 2.02 15.70 ± 2.22 17.83 ± 1.50
L 15.96 ± 5.04 20.06 ± 5.33 18.99 ± 3.12 20.44 ± 5.95
LYM (%) H 84.25 ± 2.78 81.64 ± 3.94 80.63 ± 1.32
L 80.71 ± 5.68 74.93 ± 5.84 76.43 ± 4.69 76.88 ± 6.40
MON (%) H 0.85 ± 0.07 1.73 ± 1.13 1.30 ± 0.36
L 2.84 ± 1.03 4.30 ± 1.77 3.85 ± 1.73 2.24 ± 1.18
EOS (%) H 0.20 ± 0.08 0.23 ± 0.19 0.15 ± 0.10
L 0.26 ± 0.17 0.40 ± 0.13 0.33 ± 0.10 0.16 ± 0.11
BAS (%) H 0.17 ± 0.10 0.24 ± 0.14 0.18 ± 0.16
L 0.23 ± 0.07 0.31 ± 0.22 0.41 ± 0.29 0.28 ± 0.15

a Significant difference between Til-HCO-SLN and saline treated mice, p < 0.05.

b Significant difference between blank HCO-SLN and saline treated mice, p < 0.05.

Abbreviations: H: high dose; L: low dose; WBC: white blood cells; RBC: red blood cells; HCT: haematocrit; MCV: mean corpuscular volume; HGB: hemoglobin; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration; PLT: blood platelet; MPV: mean platelet volume; PCT: plateletcrit; RDW: red cell distribution width; NEU: neutrophils; LYM: lymphocytes; MON: monocytes; EOS: eosinophils; BAS: basophils.