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. 2011 Nov 16;8:33. doi: 10.1186/1476-9255-8-33

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Copyright ©2011 Murumalla et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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SR141716A has no effect on basal adiponectin secretion, but restores basal level in LPS-treated mature adipocytes . Panel A: Mature adipocytes were treated or not with 200 nM SR141716A for 12 and 24 hours. The medium was assayed for adiponectin using ELISA. The graph shows the mean ± SD of the results from 3 patients (n = 6 for each condition, for each patient). Panel B: Mature adipocytes were treated or not with LPS 1 μg/mL, alone or in combination with 200 nM SR141716A for 24 hours. The medium was assayed for adiponectin using ELISA. The graph shows the mean ± SD of the results from 5 patients (n = 6 for each condition, for each patient). ***P < 0.001, versus control cells. ###P < 0.001, versus LPS-treated cells.