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. 2012 Jan 6;7(1):e29459. doi: 10.1371/journal.pone.0029459

Table 4. Family history and breast cancer hormone receptor status by age at diagnosis.

		ER−&PR− vs. ER+/PR+			ER− vs. ER+			PR− vs. PR+
	N of			N of			N of
	ER+/PR+ tumors			ER+ tumors			PR+ tumors
	/ER−&PR− tumors¹	OR (95% CI)²	P ²	/ER− tumors¹	OR (95% CI)²	P ²	/PR− tumors¹	OR (95% CI)²	P ²
Among <50 years old
Family history
o	98/19	1.00		97/22	1.00		74/35	1.00
Yes	40/21	2.79 (1.34–5.81)	0.006	39/23	2.66 (1.32–5.39)	0.006	36/24	1.40 (0.72–2.72)	0.32
Among 50+ years old
Family history
No	315/88	1.00		310/98	1.00		228/153	1.00
Yes	51/13	0.91 (0.48–1.76)	0.79	50/15	0.95 (0.51–1.76)	0.87	38/20	0.79 (0.44–1.40)	0.42

¹

Subjects with missing information of ER, PR, or family history were removed from analyses.

²

Results were estimated from case-only logistic regressions with adjustment for age at diagnosis.