Table 5. Family history and breast cancer subtypes further stratified by DNA ploidy.
Diploid & near-diploid | Aneuploid | ||||||
N of | ER−&PR− | ER−&PR− | |||||
ER+/PR+ tumors1 | N1 | OR (95% CI)2 | P 2 | N1 | OR (95% CI)2 | P 2 | |
Family history | |||||||
No | 413 | 21 | 1.00 | 86 | 1.00 | ||
Yes | 91 | 11 | 2.17 (0.99–4.74) | 0.053 | 23 | 1.23 (0.73–2.08) | 0.43 |
Among <50 years old | |||||||
Family history | |||||||
No | 98 | 3 | 1.00 | 16 | 1.00 | ||
Yes | 40 | 7 | 5.87 (1.43–24.06) | 0.014 | 14 | 2.21 (0.97–5.00) | 0.058 |
Subjects with missing information of ER, PR, or family history were removed from analyses.
Results were estimated from case-only logistic regressions with adjustment for age at diagnosis.