Table II.
Il10 transcription is strongly induced in CD4+FoxP3− T cells and macrophages during lupus.
| Cell population | n | % Thy-1.1+ |
|
|---|---|---|---|
| 16 wk | 5 wk | ||
| T cells | 4 | 3.97 | 2.02 |
| Tregs | 4 | 11.92 | 9.74 |
| CD4+FoxP3− T cells | 4 | 15.81 | 0.89 |
| CD8+ T cells | 4 | 0.75 | 1.08 |
| CD4−CD8− T cells | 4 | 0.52 | 2.27 |
| B cells | 4 | 0.63 | 0.10 |
| T2 B cells | 4 | 0.30 | nd |
| FOL I B cells | 4 | 0.59 | 0.03 |
| MZ B cells | 4 | 0.61 | nd |
| B10 cells | 4 | 0.94 | 0.28 |
| Plasmablasts | 4 | 2.09 | |
| cDCs | 4 | 4.86 | 0.13 |
| pDCs | 4 | 0.55 | 0.87 |
| MΠ | 4 | 12.96 | 0.53 |
| Neutrophils | 4 | 1.13 | 0.10 |
Flow cytometry of spleen single cell suspensions of 16 and 5 wk old 10BiT MRL.Faslpr mice. The data for the 16 wk old mice is the same as in bar graph Fig. 6A and is shown here in tabular form for easier comparison to the results obtained from 5 wk old animals. nd, no detectable Thy-1.1 expression.