A) Heat map showing the induction of serum cytokines, based on multiplex bead-based analysis, over baseline levels (0 h) in wild-type (WT) mice after PHx. Colored blocks represent changes at each time point, with the color intensity indicating the magnitude of the change, as indicated in the legend to the right. Cytokines are clustered based on similarity of post-PHx induction. Branches to the left of the heat map indicate similar groups; branches closer to the left edge of the heat map connect cytokines with stronger similarities, as compared to those farther out (n = 8–18 mice per time point). B) Same cluster analysis as in (A), but for cytokine induction following sham surgery (n = 5–9 mice per time point).