Table 3.
Regions Showing Significant Group by Condition Interaction Effects (p <.05, clusters ≥1344 μl) for BOLD Signal for Errors Relative to Correct Responses
| Anatomic Regionx | Brodmann Areas | Volume (μl) | Talairachx | Low LR | High LR | ||||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | Placebo Mean | Alcohol Mean | Placebo Mean | Alcohol Mean | |||
| R middle temporal gyrus, extending to the R inferior temporal gyrus | 37,21,20 | 3072 | -58 | 49 | -8 | 0.01a | -0.17b | -0.41 | 0.30 |
| L lingual gyrus, extending to the L cuneus | 18,17 | 1792 | 22 | 77 | -4 | -0.67aaa | -0.86 | -1.51aa | -0.69 |
| R declive, extending to the R uvula | -- | 1600 | -6 | 85 | -16 | -0.09aa | -0.58b | -0.63bb | 0.04 |
| L paracentral lobule, extending to the L precuneus | 5,7 | 1600 | 2 | 45 | 64 | -0.49 | -0.66a | -0.98 | 0.02 |
| L precentral gyrus, extending to the L inferior frontal gyrus | 6,9 | 1472 | 46 | 1 | 28 | -0.08 | -0.16a | -0.32 | 0.21 |
x
Talairach coordinates refer to peak effect group difference within the cluster.
Abbreviations: R right; L left; LR level of response to alcohol.
a
Follow-up t-test showing significant group differences for the condition, p<.05
b
Follow-up t-test showing significant group differences for the condition, p<.01
aa
Follow-up t-test showing significant condition effects within the group, p<.05
bb
Follow-up t-test showing significant condition effects within the group, p<.01