Table 4.

Regions Showing Significant Group or Group by Condition Effect (p <.05, clusters ≥1344 μl) in BOLD Response Contrast for Hard Relative to Easy Inhibition Trials

Anatomic Regionx	Brodmann Areas	Volume (μl)	Talairachx			Low LR		High LR
			x	y	z	Placebo Mean	Alcohol Mean	Placebo Mean	Alcohol Mean
L superior frontal gyrus, extending to the L medial frontal gyrus, L precentral gyrus, L middle frontal gyrus, L cingulate gyrus, and L paracentral lobuley	6,31,5	7360	10	1	68	0.05a	0.12b	-0.12	-0.14
L anterior cingulate, extending to L cingulate gyrus, L medial frontal gyrus, L middle frontal gyrusy	32,9,24	3968	2	-27	24	-0.04	0.10b	-0.20	-0.18
L lingual gyrus, extending to L middle occipital gyrus, L cuneusy	18,19,17	5120	18	89	-8	-0.29b	-0.25b	0.06	0.13
R cuneus, extending to the R middle occipital gyrusy	18,19	6016	-10	89	12	-0.32a	-0.30b	0.01	0.09
L angular gyrus, extending to L inferior parietal lobule and L precuneusz	39,19	2560	50	61	36	0.01aa	-0.18a	-0.21	0.13
R fusiform gyrus, extending to R lingual gyrus and R inferior occipital gyrusz	18,17	4480	-18	89	-12	0.07	-0.34a	-0.16aa	0.29

^xTalairach coordinates refer to peak effect group difference within the cluster.

Abbreviations: R right; L left; LR level of response to alcohol.

^ySignificant group (Low vs. High LR) main effect.

^zSignificant group by condition interaction effect.

^aFollow-up t-test showing significant group differences for the condition, p<.05

^bFollow-up t-test showing significant group differences for the condition, p<.01

^aaFollow-up t-test showing significant condition effects within the group, p<.05