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. Author manuscript; available in PMC: 2013 Jan 15.
Published in final edited form as: J Immunol. 2011 Dec 19;188(2):774–780. doi: 10.4049/jimmunol.1101383

Fig. 1. MyD88 is involved in phagosomal processing of GBS nucleic acids.

Fig. 1

Confocal microscopic evaluation of phagocytic processing of GBS nucleic acid (A). BMDM from wild type and MYD88-deficient mice were incubated with 106/ml labelled GBS for 0.5h; 24h or 48h. White arrow heads indicate GBS nucleic acid in phagosome. B&C. GBS were incubated with BMDM of the indicated genotypes for 24h, the cell lysates were analyzed by quantitative PCR for GBS DNA (black) and GBS RNA (gray) as outlined in the methods section; Y axis represents the amount of amplified GBS DNA or RNA relative to amount of mouse DNA. Data is mean ± SD.