Table 2.
Full cohort N=23 | OSA subjects only N=9 | |||
---|---|---|---|---|
R2 | p value | R2 | p value | |
Insulin resistance and body mass index | ||||
HOMA-IR vs. evening hsCRP | 0.00 | 0.858 | 0.76 | 0.011 |
HOMA-IR vs. morning hsCRP | 0.43 | 0.002 | 0.80 | <0.001 |
HOMA-IR vs. change hsCRP (absolute) | 0.25 | 0.025 | 0.11 | 0.477 |
HOMA-IR vs. change hsCRP (%) | 0.31 | 0.011 | 0.01 | 0.870 |
BMI z-score vs. evening hsCRP | 0.46 | 0.001 | 0.51 | 0.031 |
BMI z-score vs. morning hsCRP | 0.41 | 0.001 | 0.57 | 0.019 |
BMI z-score vs. change hsCRP (absolute) | 0.00 | 0.789 | 0.01 | 0.771 |
BMI z-score vs. change hsCRP (%) | 0.05 | 0.955 | 0.02 | 0.663 |
Inflammatory markers | ||||
Evening hsCRP vs. evening hsIL-6 | 0.68 | <0.001 | 0.71 | <0.001 |
Morning hsCRP vs. morning hsIL-6 | 0.8 | <0.001 | 0.87 | 0.003 |
Change hsCRP vs. change hsIL-6 (absolute) | 0.19 | 0.047 | 0.22 | 0.207 |
Change hsCRP vs. change hsIL-6 (%) | 0.27 | 0.015 | 0.64 | <0.001 |
Evening hsCRP vs. evening hsTNF-α | 0.01 | 0.713 | 0.15 | 0.385 |
Morning hsCRP vs. morning hsTNF-α | 0.03 | 0.489 | 0.01 | 0.848 |
Change hsCRP (%) vs. change hsTNF-α (absolute) | 0.06 | 0.323 | 0.74 | 0.028 |
Change hsCRP (%) vs. change hsTNF-α (%) | 0.14 | 0.145 | 0.40 | 0.175 |
R2 values for correlations. Items in bold are significant (p<0.025 after Bonferroni adjustment for multiple comparison)
HOMA-IR homeostasis model for insulin resistance, hsCRP high-sensitivity C-reactive protein, BMI body mass index, hsIL-6 high-sensitivity IL-6, hsTNF-α high-sensitivity TNF-α