Table 3.

[¹⁸F]WC-II-89 vs [^99mTc]mebrofenin uptake in anti-Fas antibody treated mice vs untreated controls

	Ratio of Mean %ID/g in Treated vs Control Groups (Treated:Control Ratio)
	[¹⁸F]WC-II-89		[^99mTc]Mebrofenin
	30 min	60 min	30 min	60 min

Blood	1.8^†	2.9^*^‡	1.5^*	1.5
Bone	1.3	1.3^†	1.7^*	1.3
Fat	1.1^†	2.1^†	1.2	1.3
Heart	1.6^*	2.1^*	1.3^*	1.1
Kidney	2.2^†	4.8^*	1.5	1.7^†
Liver	3.4^*	2.3^*	7.6^†	2.0
Lung	1.8^*	2.2^*	1.6	1.7^†
Muscle	1.6^*	0.6	2.1	0.2
Spleen	1.8^*	1.9^*	1.5	1.7
Thymus	1.3	1.8^†	0.8	1.2

N=4 in all groups.

%ID/g = Percent injected dose per gram of tissue

p<0.05 when comparing the mean %ID/g of the treated vs untreated control groups for each tracer

^†

p<0.10 when comparing the mean %ID/g of the treated vs untreated control groups for each tracer

^‡

Analysis for blood excludes one data point in the control group deemed contaminated (17 %ID/g vs 1.4±0.15 %ID/G for remaining 3 values in the control group for blood; %ID/g for blood from untreated controls in prior experiments was 0.8±0.1, N=4, Table 2). The treated:control ratio for the control blood including the high outlier was 0.77. The p-value was not significant if this outlier was included in the analysis.