Table 3.
Cytokine (pg/ml) | DSS treatment |
||||
---|---|---|---|---|---|
Day 0 | Day 3 | Day 6 | Day 9 | Day 12 | |
TNFα | 52.8±5.6 | 71.0±5.8* | 69.7±8.1 | 57.8±11.6 | 52.1±9.3 |
IL-1β | 35.4±8.6 | 28.5±6.0 | 39.4±11.2 | 227.5±22.7** | 144.6±16.4** |
IL-6 | 70.2±17.6 | 78.7±10.4 | 132.2±42.4*** | 430.8±109.1** | 173.4±24.0** |
IL-17A | 113.6±10.6 | 108.9±10.9 | 249.8±24.1 | 714.1±93.6** 2 | 2023.9±172.1** |
MCP-1 | 30.3±8.6 | 37.2±9.4 | 156.8±16.2** | 79.4±18.2* | 22.5±4.3 |
IFN-γ | 51.0±6.7 | 44.2±7.8 | 51.1±9.3 | 40.4±18.0 | 41.2±6.4 |
IL-12/23(p40) | 55.6±7.3 | 57.8±6.5 | 77.4±11.9* | 67.0±6.1 | 54.6±7.2 |
IL-4 | 39.5±4.2 | 43.6±7.3 | ND | ND | ND |
IL-10 | 59.2±20.9 | 133.6±16.4* | 35.5±12.8 | 30.4±11.3 | 27.2±13.6 |
GM-CSF | ND | 65.0±16.3* | 29.4±9.2 | 21.0±8.4 | ND |
p<0.05
p<0.01
p<0.001, versus respective controls.