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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Hepatology. 2011 Dec 29;55(2):437–446. doi: 10.1002/hep.24708

Figure 3. Ethanol-induced triglyceride (TG) accumulation is mediated through lipin-1 induction in AML-12 hepatocytes.

Figure 3

(A) AML-12 cells were treated with ethanol (100 mM) or inhibitors, 4-methylpyrazole (4-MP) and cyanamide (Cya), for 48 h and cellular TG levels were measured. (B) AML-12 cells were transfected with control siRNA or Lpin1siRNA. Forty-eight hours after transfection, ethanol (E; 100 mM) was added. After incubation for 48 h, cellular TG contents were measured. Data are means±SD from 3–5 experiments. Means without a common letter differ, p< 0.05.