Skip to main content
. Author manuscript; available in PMC: 2013 Jan 15.
Published in final edited form as: J Immunol. 2011 Dec 14;188(2):559–568. doi: 10.4049/jimmunol.1100335

FIGURE 6. Helminth infection of NOD mice does not reduce the Th17 immune response.

FIGURE 6

A, splenocyte production of IL-17 and (B) frequency of CD4+IL-17+ cells from spleens of uninfected (U) and L. sigmodontis-infected (L.s.) immunocompetent and IL-4-deficient NOD mice after activation with anti-CD3/anti-CD28. C, IL-17 release after anti-CD3/anti-CD28 stimulation of pancreatic lymph node cells of immunocompetent NOD mice. D, frequencies of CD4+CD17+ pancreatic lymph node cells from IL-4-deficient NOD mice. Each dot represents one mouse. Data is joined from 2–4 independent experiments. Statistical significance was assessed using the Kruskal-Wallis test, followed by Dunn’s post-hoc multiple comparisons. *p<0.05; **p<0.01