Table 2.
Characteristics of matched cases and controls.
| Characteristic | Cases | Controls | p value |
|---|---|---|---|
| Number (N) | 66 | 130 | N/A |
| CRP_A, rs3093077, G allele freq | 5/110 = 0.045 | 12/218=0.055 | 0.915* |
| CRP_B, rs1205, A allele freq | 46/108 = 0.426 | 107/224 = 0.478 | 0.442 |
| CRP_C, rs1130864, C allele freq | 28/110 = 0.256 | 50/228 = 0.219 | 0.560 |
| MBL2, rs1800451, T allele freq | 5/132 = 0.038 | 6/254 = 0.024 | 0.634 |
| IL1A, rs 3783550, G allele freq | 51/112 = 0.455 | 103/230 = 0.448 | 0.988 |
| CTLA4, rs231775, G allele freq | 58/120 = 0.483 | 114/230 = 0.496 | 0.915 |
| Age, mean years (SD) | 23.21 (5.63) | 23.74 (5.01) | 0.422** |
| Parity (N, % nulliparous) | 38 (57.6%) | 49 (37.7%) | <.001*** |
| Gestation at first prenatal visit mean wks from LMP, (SD) | 13.2 (7.5) | 13.8 (8.2) | 0.509 |
| Weight at first prenatal | 181.27 (44.96) | 157.28 (34.81) | <.001 |
| Body-Mass index (BMI) | 30.61 (6.90) | 26.99 (6.16) | <.001 |
| Gestational diabetes, N (% yes) | 11 (16.7%) | 6 (4.6%) | 0.081 |
| Weeks of gestation at delivery | 36.50 (3.93) | 39.24 (2.13) | <.001 |
| Birth weight of infant, grams | 3031 (1030) | 3393 (601) | 0.003 |
| Mother's educational attainment (years of education) | 11.87 (1.85) | 12.17 (2.17) | 0.297 |
| Maternal smoking, N (% yes) | 24/54 (44.4%) | 55/110 (50.0%) | 0.470 |
| Maternal smoking (Mean cigarettes smoked) | 5.36 (7.09) | 6.19 (11.74) | 0.523 |
| Mean systolic blood pressure | 165.2 (16.4) | 127.4 (10.6) | <.001 |
| Mean diastolic blood pressure | 97.8 (9.8) | 75.2 (7.5) | <.001 |
*
Differences in allele frequency evaluated with Chi square test
**
Differences between means evaluated with paired t test
***
Differences between discrete variables evaluated with McNemar's Chi square test