Table 1.
Selected Baseline Characteristics in Relation to Age Groups in 71,237 Women Eligible for the Analysis of All-Cause Mortality
| Age Group
|
||||||
|---|---|---|---|---|---|---|
| 36–59* n=30080 |
60–64* n=10816 |
65–69* n=10438 |
70–74* n=8143 |
75–84* n=9604 |
85–94* n=2156 |
|
| Risk Factors | ||||||
| BMI† | ||||||
| <18 | 337 (1.1) | 120 (1.1) | 114 (1.1) | 114 (1.4) | 175 (1.8) | 79 (3.7) |
| 18–22.5 | 9844 (32.7) | 2925 (27.0) | 2783 (26.7) | 2135 (26.2) | 2608 (27.2) | 699 (32.4) |
| 22.5–25 | 6771 (22.5) | 2473 (22.9) | 2404 (23.0) | 1922 (23.6) | 2202 (22.9) | 430 (19.9) |
| 25–30 | 7575 (25.2) | 3108 (28.7) | 3038 (29.1) | 2305 (28.3) | 2479 (25.8) | 372 (17.3) |
| >30 | 4769 (15.9) | 1732 (16.0) | 1507 (14.4) | 993 (12.2) | 879 (9.2) | 95 (4.4) |
| Unknown | 784 (2.6) | 458 (4.2) | 592 (5.7) | 674 (8.3) | 1261 (13.1) | 481 (22.3) |
| Smoking | ||||||
| Never | 17893 (59.5) | 5963 (55.1) | 5819 (55.8) | 4866 (59.8) | 6130 (63.8) | 1574 (73.0) |
| Former | 10214 (4.0) | 4109 (38.0) | 3922 (37.6) | 2802 (34.4) | 3052 (31.8) | 534 (24.8) |
| Current | 1973 (6.6) | 744 (6.9) | 697 (6.7) | 475 (5.8) | 422 (4.4) | 48 (2.2) |
| Alcohol | ||||||
| Never | 4745 (15.8) | 1839 (17.0) | 1999 (19.2) | 1757 (21.6) | 2379 (24.8) | 668 (31.0) |
| Former | 4250 (14.1) | 1361 (12.6) | 1381 (13.2) | 1053 (12.9) | 1405 (14.6) | 346 (16.1) |
| Current, <20 g/d | 17476 (58.1) | 5941 (54.9) | 5441 (52.13) | 4103 (50.4) | 4206 (43.8) | 746 (34.6) |
| Current, ≥20 g/d | 2687 (8.9) | 1288 (11.9) | 1150 (11.0) | 744 (9.1) | 683 (7.1) | 95 (4.4) |
| Unknown | 922 (3.1) | 387 (3.6) | 467 (4.5) | 486 (6.0) | 931 (9.7) | 301 (14.0) |
| Hormone Use and Mortality | ||||||
| Hormone therapy | ||||||
| Never | 5525 (18.4) | 2429 (22.5) | 2999 (28.7) | 2422 (29.7) | 3347 (34.9) | 1152 (53.4) |
| Former | 2658 (8.8) | 1510 (14.0) | 1859 (17.8) | 1987 (24.4) | 2845 (29.6) | 567 (26.3) |
| Current | 20111 (66.9) | 6351 (58.7) | 5030 (48.2) | 3257 (40.0) | 2848 (29.7) | 315 (14.6) |
| Other | 1786 (5.9) | 526 (4.9) | 550(5.3) | 477 (5.9) | 564 (5.9) | 122 (5.7) |
| Death | ||||||
| No | 29227 (97.2) | 10196 (94.3) | 9435 (90.4) | 6871 (84.4) | 6424 (66.9) | 685 (31.8) |
| Yes | 853(2.8) | 620 (5.7) | 1003(9.6) | 1272 (15.6) | 3180(33.1) | 1471(68.2) |
| IHD death | ||||||
| No | 30017 (99.8) | 10756 (99.5) | 10325 (99.0) | 7953 (97.7) | 8950 (93.2) | 1754 (81.4) |
| Yes | 55 (0.2) | 54 (0.5) | 110 (1.1) | 189 (2.3) | 654 (6.8) | 402(18.7) |
| Age Group
|
||||||
|---|---|---|---|---|---|---|
| 36–59* n=30174 |
60–64* n=10816 |
65–69* n=10438 |
70–74* n=8143 |
75–84* n=9604 |
85–94* n=2156 |
|
| Medical History | ||||||
| Prior heart attack | ||||||
| No | 29839 (99.2) | 10632 (98.3) | 10139 (97.1) | 7806 (95.9) | 8993 (93.6) | 1946 (90.3) |
| Yes | 156 (0.5) | 147 (1.4) | 266 (2.6) | 293 (3.6) | 542 (5.6) | 169 (7.8) |
| Unknown | 85 (0.3) | 37 (0.3) | 33 (0.3) | 44 (0.5) | 69 (0.7) | 41 (1.9) |
| Prior stroke | ||||||
| No | 29752 (98.9) | 10643 (98.4) | 10239 (98.1) | 7884 (96.8) | 9102 (94.8) | 1975 (91.6) |
| Yes | 243 (0.8) | 136 (1.3) | 166 (1.6) | 215 (2.6) | 433 (4.5) | 140 (6.5) |
| Unknown | 85 (0.3) | 37 (0.3) | 33 (0.3) | 44 (0.5) | 69 (0.7) | 41 (1.9) |
| Prior cancer | ||||||
| No | 26883 (89.4) | 9318 (86.2) | 8682 (83.2) | 6479 (79.6) | 7212 (75.1) | 1567 (72.7) |
| Yes | 3197 (10.6) | 1498 (13.9) | 1756 (16.8) | 1664 (20.4) | 2392 (24.9) | 589 (27.3) |
| Prior diabetes | ||||||
| No | 29243 (97.2 ) | 10342 (95.6) | 9909 (94.9) | 7658 (94.0) | 9016 (93.9) | 2012 (93.3) |
| Yes | 752 (2.5) | 437 (4.0) | 496 (4.8) | 441 (5.4) | 519 (5.4) | 103 (4.8) |
| Unknown | 85 (0.3) | 37 (0.3) | 33 (0.3) | 44 (0.5) | 69 (0.7) | 41 (1.9) |
| Behavioral Factors** | ||||||
| Physical activity‡, hrs/wk/yr | 3.5 ± 3.9 | 4.0 ± 4.4 | 4.2 ± 4.4 | 3.9 ± 4.4 | 3.0 ± 4.0 | 1.6 ± 3.0 |
| Dietary calories, kcal | 1603.4 ± 554.3 | 1473.8 ± 500.3 | 1458.4 ± 475.2 | 1434.9 ± 470.3 | 1426.4 ± 484.9 | 1441.9 ± 518.7 |
| Dietary calories from fat, kcal/d | 508.9 ± 243.8 | 464.6 ± 222.9 | 456.0 ± 214.4 | 449.2 ± 214.9 | 452.8 ± 217.2 | 485.4 ± 230.4 |
| Dietary calories from protein, kcal/d | 251.1 ± 95.5 | 233.1 ± 89.3 | 234.6 ± 87.7 | 232.6 ± 87.8 | 231.5 ± 90.9 | 232.1 ± 94.8 |
| Daily dietary cholesterol, mg | 194.3 ± 108.2 | 184.6 ± 106.0 | 184.0 ± 107.4 | 181.5 ± 106.4 | 184.1± 109.1 | 200.7 ± 123.4 |
*
Data presented as No. (%) for categorical variables, or mean ± SD for continuous variables.
†
BMI: body mass index, calculated as weight in kilograms divided by height in meters squared.
‡
Physical activity: combination of strenuous and moderate activities in past three years.
Note: All comparisons across age groups were significant (p<0.0001).
**
Computed on subjects with known values.