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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Am J Kidney Dis. 2011 Oct 5;59(2):284–292. doi: 10.1053/j.ajkd.2011.07.024

Figure 2.

Figure 2

Relationship of ANGPTL4 overexpression with proteinuria. (a) Albuminuria in female NPHS2-ANGPTL4 transgenic rats. (b) Albuminuria in male heterozygous NPHS2-ANGPTL4 transgenic rats. (c) Albuminuria in male homozygous NPHS2-ANGPTL4 transgenic rats. (d) Gel electrophoresis of urinary protein from wild-type (WT) rats, transgenic (TG) rats, PAN (puromycin aminonucleoside nephrosis) rats, and individuals with minimal change disease (MCD) and membranous nephropathy (MN). Arrow points towards prominent 70 kDa intact albumin band. Mean percentage densitometry of intact albumin is shown for each lane. * P<0.05, ** P<0.01, *** P<0.001. Abbreviations: NPHS2, podocin; ANGPTL4, angiopoietin-like 4. Reproduced from Clement et al9.