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. 2011 Jul 28;1(2):185–199.

Table 1.

Causes of AS. Wide frequency range generally reflects the age group(s) assessed by individual studies as well as population subgroups studied [79, 115-117].

Etiology Approximate frequency (%) Associated features
Aging/calcific 50 - 70 Increased risk of coronary events.
Bicuspid aortic valve 6 - 40 Dilatation or dissection of the aorta, involving the aortic root, ascending aorta, or aortic arch.
Rheumatic 2 - 11 Mitral valve almost always affected as well
Unicuspid aortic valve <1 Dilatation or dissection of the aorta, involving the aortic root, ascending aorta, or aortic arch.
Post-endocarditis <1 Extra-cardiac embolic phenomena.