Table 4. GROUP DIFFERENCES.

Consistent differences in brain regions activated activations during supraliminal rectal balloon inflation in IBS patients compared to controls.

IBS > HEALTHY CONTROL
	Region	Hemisphere	Volume mm3	ALE Value	x	y	z
1	Midbrain	R/L	1704	0.0173	0	−28	−8
	Thalamus (medial dorsal nucleus)	L		0.0131	−2	−20	2
2	Thalamus	R	1672	0.0150	10	−14	0
3	mINS	R	1256	0.0161	40	8	8
4	SMA (BA 6)	R	920	0.0153	2	8	48
5	Amygdala	L	536	0.0123	−24	−4	−12
6	pACC (BA 24)	R	472	0.0107	6	36	2
7	Putamen	R	400	0.0128	18	4	6
8	aINS	L	368	0.0104	−36	20	0
9	aMCC (BA 32)	R	328	0.0112	0	18	36
10	aINS	L	312	0.0114	−46	0	0
11	aMCC (BA 24)	L	288	0.0103	−14	4	34
12	aMCC (BA 24)	R	240	0.0109	2	10	26
HEALTHY CONTROL >IBS
	Region	Hemisphere	Volume mm3	ALE Value	x	y	z
1	aINS	R	1344	−0.0107	36	22	0
2	Thalamus (pulvinar)	R	1312	−0.0174	8	−26	8
3	Putamen	L	1080	−0.0134	−22	−2	12
4	aINS	L	968	−0.0173	−38	10	6
5	Dorsolateral prefrontal cortex (BA 9/46)	L	776	−0.0126	−26	42	26
6	Inferior parietal lobule (BA 40)	L	664	−0.0153	−56	−20	24
7	Pre/Post central gyrus (BA 43)	R	344	−0.0107	58	−8	14
8	Inferior parietal lobule (BA 40)	R	168	−0.0104	52	−30	30
9	Medial prefrontal cortex (BA 9/32)	R	144	−0.0095	12	32	34