Table 2.
Coefficient estimates (posterior log-hazard ratios) and 95% credible intervals from piecewise exponential proportional hazards model for all-cause mortality in the Long Island Breast Cancer Study Project under different missing data assumptions.
| Posterior estimate of β (95% credible interval) | ||||||
|---|---|---|---|---|---|---|
| Variable | Complete Casea (n=499) |
MARb (n=1436) |
NMAR 1c (n=1436) |
NMAR 2d (n=1436) |
NMAR 3e (n=1436) |
|
| Change in bodyweight | ||||||
| >5% loss | 1.50 (0.93, 2.07) | 1.65 (1.25, 2.07) | 1.67 (1.27, 2.08) | 1.66 (1.27, 2.08) | 1.65 (1.26, 2.06) | |
| 5–10% gain | −0.12 (−1.14, 0.79) | 0.12 (−0.64, 0.80) | 0.07 (−0.67, 0.77) | 0.08 (−0.68, 0.77) | 0.07 (−0.69, 0.77) | |
| >10% gain | 0.56 (−0.28, 1.38) | 1.22 (0.60, 1.81) | 1.00 (0.34, 1.63) | 1.01 (0.33, 1.63) | 0.99 (0.33, 1.62) | |
| Chemotherapy treatment | 0.58 (0.02, 1.15) | 0.67 (0.31, 1.02) | 0.67 (0.32, 1.03) | 0.68 (0.33, 1.03) | 0.68 (0.33, 1.03) | |
| ER positive tumor | −0.66 (−1.28, −0.04) | −0.51 (−0.86, −0.16) | −0.52 (−0.87, −0.17) | −0.52 (−0.87, −0.16) | −0.52 (−0.86, −0.16) | |
| PR positive tumor | −0.30 (−0.89, 0.31) | −0.29 (−0.61, 0.05) | −0.29 (−0.62, 0.04) | −0.29 (−0.62, 0.04) | −0.29 (−0.61, 0.04) | |
| Tumor size > 2cm | 0.63 (0.13, 1.13) | 0.66 (0.36, 0.95) | 0.67 (0.37, 0.96) | 0.67 (0.36, 0.96) | 0.66 (0.37, 0.96) | |
| Age at diagnosis | 0.04 (0.02, 0.07) | 0.04 (0.03, 0.06) | 0.04 (0.03, 0.06) | 0.04 (0.03, 0.06) | 0.04 (0.03, 0.05) | |
Excludes subjects with missing data on one or more covariates.
Specifies model for distribution of missing covariates.
Specifies model for distribution of missing covariates and missing data indicator for change in bodyweight. Precision 10−6 on beta.
Specifies model for distribution of missing covariates and missing data indicator for change in bodyweight. Precision 10−3 on beta.
Specifies model for distribution of missing covariates and missing data indicator for change in bodyweight. Precision 10−1 on beta.