Figure 1. Dose dependent increase and rapid clearance of total SFN metabolites in most wild-type mouse tissues.
(A) Male and female wild-type mice received gavage of either 5 (open bars) or 20 (solid bars) µmoles of SFN and tissues were collected at 2, 6, and 24 h. Data in graphs represent the mean ± SEM of the sum of all SFN metabolites normalized to tissue weight (n=12 for all tissues except prostate; prostate n=6). (B) Two-way ANOVA analysis of the data.