Skip to main content
. 2012 Jan 9;7(1):e29389. doi: 10.1371/journal.pone.0029389

Figure 2. Effect of leptin on the intracellular location of GLUT4 protein in skeletal muscle.

Figure 2

Representative images of GLUT4 immunostaining in sections of the gastrocnemius, extensor digitorum longus (EDL) and soleus of wild type (WT), control ob/ob (OB), pair-fed ob/ob (PF) and leptin-treated ob/ob (LE) mice. Larger-magnification images within black frames of immunohistochemical staining for GLUT4 in gastrocnemius, EDL and soleus sections of leptin-treated ob/ob mice are shown. Arrows indicate punctuate distribution of GLUT4 vesicles in plasma membrane and cytosol of muscle sections. Scale bars = 50 µm.